1 | Saudi Arabia | Burns | Chitosan topical gel formulation in the management of burn wounds | 2009 | Gel / Hydrogel | Research Publication | Animal |
2 | US | Burns | Chitosan Acetate Bandage as a Topical Antimicrobial Dressing for Infected Burns▿ | 2009 | Wound Dressing | Research Publication | Animal |
3 | Brazil | Burns | Improvement of dermal burn healing by combining sodium alginate/chitosan-based films and low level laser therapy | 2011 | Films | Research Publication | Animal |
4 | China | Burns | Hydrogel sheets of chitosan, honey and gelatin as burn wound dressings | 2012 | Gel / Hydrogel | Research Publication | Animal |
5 | Algeria | Burns | Evaluation of healing activity of PVA/chitosan hydrogels on deep second degree burn: pharmacological and toxicological tests | 2013 | Gel / Hydrogel | Research Publication | Animal |
6 | Brazil | Burns | Microparticles of Aloe vera/vitamin E/chitosan: Microscopic, a nuclear imaging and an in vivo test analysis for burn treatment | 2014 | Other / Multiple | Research Publication | Animal |
7 | Taiwan | General Wounds | Assessment of reinforced poly(ethylene glycol) chitosan hydrogels as dressings in a mouse skin wound defect model | 2013 | Gel / Hydrogel | Research Publication | Animal |
8 | Turkey | Burns | Chitosan gel formulations containing egg yolk oil and epidermal growth factor for dermal burn treatment | 2015 | Gel / Hydrogel | Research Publication | Animal |
9 | China | Spinal Cord injury | NT3-chitosan elicits robust endogenous neurogenesis to enable functional recovery after spinal cord injury | 2015 | Other / Multiple | Research Publication | Animal |
10 | Iran | Ulcers | Potential application of nanochitosan film as a therapeutic agent against cutaneous leishmaniasis caused by L. major | 2015 | Films | Research Publication | Animal |
11 | Iran | Burns | Chitosan gel-embedded moxifloxacin niosomes: An efficient antimicrobial hybrid system for burn infection | 2016 | Gel / Hydrogel | Research Publication | Animal |
12 | China | Burns | On-Demand Dissolvable Self-Healing Hydrogel Based on Carboxymethyl Chitosan and Cellulose Nanocrystal for Deep Partial Thickness Burn Wound Healing | 2018 | Gel / Hydrogel | Research Publication | Animal |
13 | Iran | Burns | Bromelain-loaded chitosan nanofibers prepared by electrospinning method for burn wound healing in animal models | 2019 | Other / Multiple | Research Publication | Animal |
14 | Pakistan | General Wounds | Silver nanoparticle impregnated chitosan-PEG hydrogel enhances wound healing in diabetes induced rabbits | 2019 | Gel / Hydrogel | Research Publication | Animal |
15 | China | Others (Endometrial Injury) | Controlled releasing of SDF-1α in chitosan-heparin hydrogel for endometrium injury healing in rat model | 2020 | Gel / Hydrogel | Research Publication | Animal |
16 | Iran | Burns | Efficacy of topical platelet-rich plasma and chitosan co-administration on Candida albicans-infected partial thickness burn wound healing | 2020 | Gel / Hydrogel | Research Publication | Animal |
17 | Iran | General Wounds | Wound healing with alginate/chitosan hydrogel containing hesperidin in rat model | 2020 | Gel / Hydrogel | Research Publication | Animal |
18 | Brazil | Ulcers | A new waterborne chitosan-based polyurethane hydrogel as a vehicle to transplant bone marrow mesenchymal cells improved wound healing of ulcers in a diabetic rat model | 2020 | Membranes | Research Publication | Animal |
19 | Brazil | Burns | Carboxymethyl chitosan hydrogel formulations enhance the healing process in experimental partial-thickness (second-degree) burn wound healing | 2021 | Gel / Hydrogel | Research Publication | Animal |
20 | China | Others (Multiple Wounds) | Effects of chitosan-collagen dressing on wound healing in vitro and in vivo assays | 2021 | Wound Dressing | Research Publication | Animal |
21 | China | Burns | Chitosan degradation products promote healing of burn wounds of rat skin | 2022 | Other / Multiple | Research Publication | Animal |
22 | China | Spinal Cord injury | Chronic spinal cord injury repair by NT3-chitosan only occurs after clearance of the lesion scar | 2022 | Gel / Hydrogel | Research Publication | Animal |
23 | Chile | Others (Multiple Wounds) | Chitosan composite films. Biomedical applications | 2008 | Films | Research Publication | Human
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24 | Iran | Burns | The effect of chitosan-based gel on second degree burn wounds | 2016 | Gel / Hydrogel | Research Publication | Human |
25 | India | Traumatic Wounds | Assessing the Efficacy of Haemostatic Dressing Axiostat® In Trauma Care at a Tertiary Care Hospital in India: A Comparison with Conventional Cotton Gauze | 2016 | Wound Dressing | Research Publication | Human |
26 | US | Burns | The use of a chitosan dressing with silver in the management of paediatric burn wounds: a pilot study | 2017 | Wound Dressing | Research Publication | Human |
27 | Malaysia | Traumatic Wounds | Efficacy of chitosan derivative films versus hydrocolloid dressing on superficial wounds | 2018 | Films | Research Publication | Human |
28 | Malaysia | Ulcers | Nano-colloidal silver and chitosan bioactive wound dressings in managing diabetic foot ulcers: case series | 2018 | Gel / Hydrogel | Research Publication | Human |
29 | Mexico | Ulcers | Chitosan treatment for skin ulcers associated with diabetes | 2018 | Films | Research Publication | Human |
30 | Mexico | Ulcers | Efficacy and safety of the combination of isosorbide dinitrate spray and chitosan gel for the treatment of diabetic foot ulcers: A double-blind, randomized, clinical trial | 2018 | Gel / Hydrogel | Research Publication | Human |
31 | Iran | Ulcers | Chitosan‑based biocompatible dressing for treatment of recalcitrant lesions of cutaneous leishmaniasis: A pilot clinical study | 2019 | Films | Research Publication | Human |
32 | Mexico | Ulcers | Characterization and efficacy of chitosan membranes in the treatment of skin ulcers | 2019 | Membranes | Research Publication | Human |
33 | Spain | Others (Dental Inflammation) | Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial | 2020 | Gel / Hydrogel | Research Publication | Human |
34 | China | Burns | Study on scar repair and wound nursing of chitosan-based composite electrospun nanofibers in first aid of burn | 2021 | Other / Multiple | Research Publication | Human |
35 | Thailand | Others (Skin Sebum) | The Efficacy and Safety of Chitosan on Facial Skin Sebum | 2021 | Gel / Hydrogel | Research Publication | Human |
36 | China | Burns | Application and clinical efficacy of Sufu medical chitosan hydrogel dressing in radiation skin damage caused by radiotherapy for cervical cancer | 2022 | Gel / Hydrogel | Research Publication | Human |
37 | China | Others (Chronic refractory wounds) | Clinical efficacy of chitosan-based hydrocolloid dressing in the treatment of chronic refractory wounds | 2022 | Wound Dressing | Research Publication | Human |
38 | India | Ulcers | Use of Chitosan-based Dressings for the Management of a Chronic Lower Limb Ulcer: A Case Report | 2022 | Wound Dressing | Research Publication | Human |
39 | China | Burns | Clinical efficacy of wet dressing combined with chitosan wound dressing in the treatment of deep second‐degree burn wounds: A prospective, randomised, single‐blind, positive control clinical trial | 2023 | Wound Dressing | Research Publication | Human |
40 | Malaysia | General Wounds | A Prospective Multicenter Randomized Controlled Trial to Evaluate the Efficacy of Chitosan Hydrogel Paste in Comparison to Commercial Hydroactive Gel as a Wound Bed Preparation | 2023 | Gel / Hydrogel | Research Publication | Human |
41 | India | Others (Multiple Wounds) | Drug loaded thermoresponsive and cytocompatible chitosan based hydrogel as a potential wound dressing | 2011 | Gel / Hydrogel | Research Publication | In vitro |
42 | Portugal | Others (Multiple Wounds) | Chitosan drives anti-inflammatory macrophage polarisation and pro-inflammatory dendritic cell stimulation | 2012 | Other / Multiple | Research Publication | In vitro |
43 | South Korea | Others (Drug resistant bacteria) | Antimicrobial Action of Water-Soluble β-Chitosan against Clinical Multi-Drug Resistant Bacteria | 2015 | Other / Multiple | Research Publication | In vitro |
44 | India | Infected Wound | Cefuroxime conjugated chitosan hydrogel for treatment of wound infections | 2019 | Gel / Hydrogel | Research Publication | In vitro |
45 | Pakistan | Others (Multiple Wounds) | Stimuli responsive biopolymer (chitosan) based blend hydrogels for wound healing application | 2019 | Gel / Hydrogel | Research Publication | In vitro |
46 | India | Others (Multiple Wounds) | Preparation and characterization of chitosan/pectin/ZnO porous films for wound healing | 2020 | Films | Research Publication | In vitro |
47 | India | Others (Efficiency on L929 Fibroblast) | Evaluation of curcumin-loaded chitosan nanoparticles for wound healing activity | 2023 | Other / Multiple | Research Publication | In vitro |
48 | US | Burns | Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects | 2011 | Other / Multiple | Review Publication | Mixed |
49 | India | Others (Multiple Wounds) | Biomaterials based on chitin and chitosan in wound dressing applications | 2011 | Other / Multiple | Review Publication | Mixed |
50 | South Korea | Traumatic Wounds | In Situ Forming and Rutin-Releasing Chitosan Hydrogels As Injectable Dressings for Dermal Wound Healing | 2011 | Gel / Hydrogel | Review Publication | Mixed |
51 | Romania | Others (Multiple Wounds) | Chitosan as a starting material for wound healing applications | 2015 | Other / Multiple | Review Publication | Mixed |
52 | India | Others (Multiple Wounds) | Chitosan Based Scaffolds and Their Applications in Wound Healing | 2016 | Other / Multiple | Review Publication | Mixed |
53 | India | General Wounds | Chitosan based metallic nanocomposite scaffolds as antimicrobial wound dressings | 2018 | Scaffold | Review Publication | Mixed |
54 | China | Others (Multiple Wounds) | A functional chitosan-based hydrogel as a wound dressing and drug delivery system in the treatment of wound healing | 2018 | Gel / Hydrogel | Review Publication | Mixed |
55 | Iran | General Wounds | http://Chitosan/alginate hydrogels containing Alpha-tocopherol for wound healing in rat model | 2019 | Gel / Hydrogel | Research Publication | Mixed |
56 | China | Infected Wound | Injectable hydrogel composed of hydrophobically modified chitosan/oxidized-dextran for wound healing | 2019 | Gel / Hydrogel | Research Publication | Mixed |
57 | India | | Chitosan and gelatin-based electrospun fibers for bone tissue engineering | 2019 | Scaffold | Review Publication | Mixed |
58 | Egypt | Others (Multiple Wounds) | Soft hydrogel based on modified chitosan containing P. granatum peel extract and its nano-forms: Multiparticulate study on chronic wounds treatment | 2019 | Gel / Hydrogel | Research Publication | Mixed |
59 | China | Traumatic Wounds | Enhanced cutaneous wound healing by functional injectable thermo-sensitive chitosan-based hydrogel encapsulated human umbilical cord-mesenchymal stem cells | 2019 | Gel / Hydrogel | Research Publication | Mixed |
60 | China | Traumatic Wounds | Preparation of Antimicrobial Hyaluronic Acid/Quaternized Chitosan Hydrogels for the Promotion of Seawater-Immersion Wound Healing | 2019 | Gel / Hydrogel | Research Publication | Mixed |
61 | China | Traumatic Wounds | Quaternized chitosan-Matrigel-polyacrylamide hydrogels as wound dressing for wound repair and regeneration | 2019 | Gel / Hydrogel | Research Publication | Mixed |
62 | China | General Wounds | Modulating cationicity of chitosan hydrogel to prevent hypertrophic scar formation during wound healing | 2020 | Gel / Hydrogel | Research Publication | Mixed |
63 | South Africa | Others (Multiple Wounds) | Chitosan and Cellulose-Based Hydrogels for Wound Management | 2020 | Gel / Hydrogel | Review Publication | Mixed |
64 | Romania | Infected Wound | Preparation and Antimicrobial Activity of Chitosan and Its Derivatives: A Concise Review | 2021 | Other / Multiple | Review Publication | Mixed |
65 | China | Others (Multiple Wounds) | Chitosan-Based Functional Materials for Skin Wound Repair: Mechanisms and Applications | 2021 | Gel / Hydrogel | Review Publication | Mixed |
66 | India | Others (Progressive Wounds) | Chitosan/Hyaluronic acid/Alginate and an assorted polymers loaded with honey, plant, and marine compounds for progressive wound healing-Know-how | 2021 | Other / Multiple | Review Publication | Mixed |
67 | Mexico | Burns | The use of chitosan as a skin-regeneration agent in burns injuries: A review | 2022 | Other / Multiple | Review Publication | Mixed |
68 | Nigeria | Others (Multiple Wounds) | A short review on chitosan and gelatin-based hydrogel composite polymers for wound healing | 2022 | Gel / Hydrogel | Review Publication | Mixed |